(5) Best Nootropics and Brain Supplements to Boost Mental Performance

Right now a lot of people are finding brain support through nootropics. These are brain supplements that are specifically made for helping cognitive memory, function, anxiety relief and more.

Before you buy brain supplements, keep in mind that highest quality nootropics should include at least a formulation of two or more following ‘must-have’ ingredients.

  1. Alpha GPC

Choline alfoscerate (Alpha-GPC) is L-a-glyceryl phosphorylcholine (GPC). This substance offers many benefits, and most of these are related to mental clarity, heightened focus and improved ability in learning.

As Alpha GPC stimulates acetylcholine receptors in the hippocampus, the neuroplasticity is enhanced thus, increasing synapses between neurons and directly affecting an individual’s capacity to pick up information.

  1. Ginkgo Biloba

Ginkgo Biloba is a combination of essential compounds, such as flavonoids (ginkgo-flavone glycosides) and terpenes (ginkgolides and bilobalide).

Over 400 published studies in the past 20 years have demonstrated that these substances produce positive effects to improve mental performance.

Ginkgo Biloba works to neutralize free radicals and improve circulation by dilating small blood vessels, thereby protecting brain cells against damage caused by oxygen deprivation.

  1. Bacopa Monnieri

Studies have specifically focused on Bacopa extract’s beneficial mechanisms on brain function, and positive findings have been reported recently in areas such as the enhancement of learning skills, enhancement in the mood, improvement in short-term and long-term memory, and reduction in adult ADHD symptoms. Results are often noticed within several hours or days depending on your sensitivity to herbs.

  1. Phosphatidylserine

Phosphatidylserine is a phospholipid or a form of fat which is most commonly located in the brain where it helps to keep cell membranes fluid, flexible and prepared for nutrient absorption.

Phosphatidylserine aids nerve tissue; for example, it supports the correct release and reception of acetylcholine and dopamine within the brain. Phosphatidylserine makes it possible for the steady performance of your memory-related pathways.

  1. Acetyl L-Carnitine

Acetyl-L-Carnitine, or also known as ALCAR, is a form of L-Carnitine that is acetylated, so it is even more powerful than L Carnitine. Because Acetyl-L Carnitine can easily cross the blood-brain barrier and thus enter the brain blood circulation, it is very effective in protecting brain cells from deterioration.

It has been demonstrated that a regular dietary supplement of Acetyl Carnitine can protect the brain from cerebral ischemia and may aid in the recovery of injured peripheral nerve.

As one of the most important neutron transmitters, Acetyl-L Carnitine is vital in enabling a person to memorize or learn anything.

One thing to note is that having more complete ingredients doesn’t mean that the products are more superior to others.

Other factors such as customer satisfaction, Good Manufacturing Practice (GMP), and company credibility should be taken into consideration as well.

Top (5) Best Brain Supplements (Nootropics)

There are many companies that are putting out supplements, but five of them are getting the most reviews.

The following 5 are the best nootropics supplements you can get, which include: Noocube, Nitrovit, Simple Smart Science, Lumonol, and Excelerol. Each one has a proprietary blend and line up of supplements.

They each offer unique options to help with brain function. The following breakdown highlights the ingredients, effectiveness, and reviews that each provides.

1. Noocube

Noocube has a superior formula that was researched for more than over 10 years by neuroscientists. This is a BSCG Certified solution that has been tested in clinical trials and promoted by world-class athletes. You may hear celebrity endorsements from UFC fighters, and even comedian Joe Rogan.

The main focal point of their blends is 100% herbal, natural ingredients, pharmaceutical grade, without fillers. They focus on research, not just promotion, and it shows.

Noocube Ingredients

  • Alpha GPC
  • Huperzine A
  • Cat’s Claw
  • Bacopa
  • Oat Straw
  • L-Theanine & L-Tyrosine
  • Vinpocetine
  • AC-11
  • Pterostilbene


The reviews indicate whether or not this option works. As far as Alpha Brain is concerned, the main reason it works is that of the blend that they have put into it. Each one helps the brain concentrate, reduce pressure, and increase balance for thoughts. With an additional Cat’s Claw boost, energy is delivered, and antioxidants help with raisin brain cell activity. Simply put, this is meant for concentration and focus. Focus supplements like this one help with more than just “one” thing, mind you. Reviews are mostly positive.

2. Nitrovit

ProjectNooYou has a product known as Nitrovit. This is a solution that ranks high amidst focus pills, and focus supplements. What you’ll find with it is an intricate blend of natural elements that are meant to help with anxiety relief, cognitive memory, and concentration.

It is not entirely similar to other smart drugs because the components are formed to stimulate ATP Energy, which is helpful to improve your brain’s health.

The company has formulated this option to be unlike other brain booster pills because it mixes energy elements, nootropic drugs, and more, in a natural capacity.

Nitrovit Ingredients

  • Noopept
  • N Acetyl L-Tyrosin
  • Theobromine
  • Huperzine
  • Alpha GPC (Choline)
  • Alpha Lipoic Acid
  • Phosphatidylserine
  • ALCAR (Acetyl L-Carnitine)
  • Vitamin B6 (Pyridoxine)
  • Vit B12 (Methylcobalamin)
  • Uridine
  • Bacopa Leaf Powder
  • CDP Choline


The reviews are mostly positive about this option. The main reason why people are so confident is that it delivers an incredible boost of energy. Throughout 6 weeks, the natural brain function of individuals rose by a lot of percentage points.

Clinical studies also prove that the elements mixed together work with anti-anxiety, ADHD symptoms, and mental capacity. Academics will find that memory can build, reasoning can build, and focus will be easy as well.

3. Excelerol

Excelerol touts itself as a unique solution for brain and cognitive function. Their official stance is that they are the right supplement for helping brain function, and it could very well be true for some.

The ingredients are natural, herbal, and are listed amongst the best brain supplements.

As you look into brain enhancing pills, you may find that the ingredient lists are going to tell the story and this one does just that. It gives you energy, it delivers nootropics, and helps brain function through natural means.

Excelerol Ingredients

  • Huperzine
  • Vitamin B-12
  • Niacin
  • Vinpocetine
  • Acetyl L-Carnitine
  • Gingko Biloba
  • Bacopa Monnieri Extract
  • Guarana Extract
  • L-Tyrosin
  • Green Tea Extract
  • DMAE


The reviews are mostly positive for this solution, mainly from students and people that have tested it for academia. As far as academic boosts are concerned, this option helps through giving energy boosts with the vitamins, and help with neurological support with the herbal solutions. It helps with mood enhancement, and brain capacity, as well as alertness as well. It does all of this without side effects, although there is a warning about blood pressure on their bottle.

4. Lumonol

Lumonol has become one of the best nootropics in the market since 2015 and is universally designed for senior, athletes, and even children. This is a solution that promises to deliver better neurotransmission in the brain.

It is listed amidst the best natural nootropics because of the ingredient list, and the reviews are mostly positive. Brain booster pills can sometimes have filler, but Lumonol has worked hard to have purity in their ingredients.

Each element helps with cognitive memory, anti-anxiety, and alleviates ADHD symptoms. Those that are trying to improve memory, or want to be more alert will find that this is a natural solution that boosts energy, function, and more.

Lumonol Ingredients

  • Noopept
  • Ginkgo Biloba
  • Alpha GCP
  • Acetyl L-Carnitine
  • L-Tyrosin
  • Phosphatidylserine
  • Panax Ginseng
  • Hordenine
  • Guarana


Looking at reviews, you’ll regularly see natural nootropics with similar ingredients, but studies have backed this option, and reports note no side effects.

Beyond noopept, this solution brings to the forefront of brain supplements that work fast, and without fatigue.

There’s no stimulants, no major issues, and reviews are generally positive from those that have tested it out.

If you’re looking for a boost in brain function, this option has a lot to offer, according to reviews and clinical studies.

5. Simple Smart Science

Simple Smart Science has a blend of ingredients for both day and night. It’s meant to help with focus, mood enhancement, and anxiety reduction. The secret to their formula relies heavily on taking both options throughout the day.

Their main release is known as Mind Boost. The day formula helps with energy, concentration, anxiety reduction, and brain function.

As far as brain supplements are concerned, this has a morning and night solution which is different than other brain pill options you may find.

Simple Smart Science Ingredients

The ingredient list on for the day solution include:

  • Bacopa Monnieri
  • Rhodiola Rosea
  • Ginkgo Biloba
  • Vitamin B12
  • Folic Acid
  • Citicoline

Night Formula Ingredients Include:

  • Picamilon
  • Olive Leaf Extract
  • Green Tea
  • Folic Acid


The reviews on this solution are mostly positive. The two nootropic supplements help with morning wake up, and evening sleep.

It is more than just your average cognitive enhancers; it helps deliver natural, herbal brain support, throughout the day. Simply put, it’s meant to give your mornings a boost, and your evening’s relaxation.

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