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Researchers find common morning sickness drug ineffective
A pill routinely taken by millions of pregnant women for getting rid of morning sickness may not be as effective as it claims to be, a new research suggested.
The morning sickness drug called pyridoxine-doxylamine, which is sold as Diclegis in the United States and as Diclectin in Canada, has been in use since the 1970s. An older version of the drug has been used since the 1950s.
Study co-author Dr. Navindra Persaud, of St. Michael’s Hospital and Canada’s University, and colleagues reviewed data from a decades-old trial and found little evidence that the drug is effective.
Sharing findings of the study, Persaud said, “This medication is recommended as the first-line treatment for nausea and vomiting during pregnancy. We now have more information about this 1970s study that should make us question whether this medication should have been approved and whether it was ever proven to be effective.”
But some experts argued that the findings mayn’t be reliable because the study’s final results aren’t available and 37 per cent of around 2,300 pregnant participants dropped out before the study ended.
The researchers reported their findings in the most recent issue of the PLOS One, a peer-reviewed, open-access journal that reports scientific studies from all disciplines.